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John H. Zhang, MD, PhD

This timely textbook is the first ever to be published on hyperbaric oxygen and its potential applications in neurological diseases. The stellar list of 37 national and international contributors is more than impressive.

Hyperbaric oxygen (HBO) has been used as a therapeutic or an alternative therapeutic strategy for neurological diseases for many years. However, for most neurological diseases, HBO is being used without FDA and UHMS approval and therefore HBO is used to treat neurological diseases in mostly free-standing clinics. One of the key issues that prevented HBO to become part of mainstream medicine for neurological diseases is the lack of scientific evidence to support a possible neuroprotective effect of HBO. That is the reason for publishing this book.

This book has four features. First, a basic science section of four chapters to demonstrate the effect of HBO on brain physiology and metabolism as well as pathophysiology. Lacking basic mechanisms for the effect of HBO has been the major hurdle preventing the use of HBO for neurological diseases.

Second, this book emphasizes the potential use of HBO in stroke treatment with three chapters, because stroke is the third leading cause of death and the leading cause of long term disability in the nation. Targeting stroke has the potential to take HBO to a new level in future applications.

Third, the experimental application of HBO is discussed with five chapters on traumatic brain injury, cerebral palsy, autism, multiple sclerosis, and on amyotrophic lateral sclerosis. There are tremendous debates in these fields and this book will provide a forum for extensive discussions.

Fourth, several FDA approved HBO applications are presented in three chapters on carbon monoxide poisoning and on radiation-induced neurological injury.

Using an old Chinese phrase “throwing a piece of rock to attract a gem quality of jadeâ€, this book is a first effort to bring experts from all over the world in the HBO community to target neurological diseases. We hope this is just a beginning, and that more books on HBO in neurological diseases will be published in the future.

Hardcover, 445 pgs)

This textbook, therefore, becomes an important reference point for clinicians, researchers and others who care for these difficult conditions and underwrite related health care costs. It is hoped that this textbook will also serve to stimulate further scientific scrutiny. These unfortunate patients are certainly that deserving. --Dick Clarke, Director “ The Baromedical Research Foundation, Columbia, SC

"Long used in a variety of therapies, this technique has found limited expression in neurology due to the lack of evidence to support a possible neuro-protective effect. These 19 chapters should alleviate this logjam and promote the use of hyperbaric oxygen (HBO) in mainstream medicine covering basic science, stroke treatment and experimental applications."
Book News, Inc. - July 2008

"This book is a very useful reference for clinicians who care for patients with these debilitating processes, and act to stimulate further discussion and scientific investiation. This is the first text on the subject and may serve as a point of reference for both researchers and clinicians."
-Neurology Journal, Harry T. Whelan, MD

Brain Physiology and HBO Cerebral Physiology and HBO Cerebral Tissue Oxygenation Mechanisms of HBO for Neurological Disorders Oxygen Therapy for Ischemic Stroke HBO for Stroke HBO for Hemorrhagic Brain Injury HBO for Traumatic Brain Injury A Clinical Appraisal of the Use of HBOT in the Treatment of Acute Traumatic Brain Injury The Use of HBOT in Autism The Case for Hyperbaric Oxygenation in Multiple Sclerosis HBO for Multiple Sclerosis HBO in Amyotrophic Lateral Sclerosis HBO for Cerebral Palsy Pathophysiology of Carbon Monoxide Toxicity HBO for Delayed Carbon Monoxide Toxicity HBO for Radiation Neurological Injury HBO for Neurological Disorders in China Hypoxic-Ischemic Encephalopathy of the Neonate Index

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